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Here is an oldie but goodie, an interview with Scott Blakey a.k.a Shanti baba. We at Shifa work closely with Shantibaba, he is the only one we trust when it comes to making our CBD Products. He is known and praised in the "weed world" but maybe not so many other know his story, here is Skunk Magazines interview with Shantibaba done back in 2016.       
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Poor sleep is a risk factor for serious illness. Compared to people who get enough sleep, adults who are short-sleepers (less than 7 hours per 24-hour period) are more likely to experience one or more of 10 chronic health conditions, including obesity, heart disease, diabetes, arthritis, stroke and depression.  Although sleep is essential for our health, its biological purpose is not fully understood. Oddly, the seemingly inactive state of sleep is actually a dynamic and critical process that helps us store memories, build immunity, repair tissue, regulate metabolism and blood pressure, control appetite and blood sugar, and process learning, along with a myriad of other physiological processes — all of which are regulated by the endocannabinoid system (ECS).
read more at PROJECT CBD Nearly half of users in the study said they’d completely stopped taking a pharmaceutical drug because of medical marijuana. As more states in America legalize marijuana, a new study shows that many patients are choosing medical cannabis to supplement or even replace pharmaceutical drugs. The study comes from the University of Michigan Institute for Social Research, which surveyed 450 adults who identified as current cannabis users. Among those surveyed, 78 percent said they used cannabis to treat a medical or health condition.  We at Shifa beleive in the whole plant as a medicine and hope that one day it will be legalized for all here in Europ as well.
Full spectrum, wide spectrum, broad spectrum, isolates. The CBD industry has several terms when promoting their products. But what do they all really mean? Here we will try to make it easier to understand and navigate in the jungle that is CBD products.  Let's start with the most used term out there, Full Spectrum. First let’s just make one thing clear, full spectrum does not mean that the product contains all cannabinoids out there. No product does. There are over 100 different cannabinoids found so far in different cannabis plants and many different terpenes as well. No product or cannabis plant out there contains all of them at once. So what do they actually mean when the label says Full Spectrum? Full Spectrum simply refers to the whole plant being used for making the CBD extract they use in their product. In other words, it’s not just a CBD isolate ( often referred to as CBD Crystals ) or other cannabinoid isolates used. But that is it, that is all it tells you. It does not say anything about which cannabinoids that are to be found in the extract and how much of it. Most laboratories don’t even have the testing equipment to test all the different cannabinoids, and focus mainly on testing the most abundant cannabinoids found in the cannabis plants. How can you know which cannabinoids that are in fact in a Full Spectrum product? The only way to know what is in the product, is to see the lab results from the producers. Or to get it tested yourself. You need to see the lab report from the laboratory, not just what a company says on the bottle or in their description. You want the actual lab report. Any serious company should have some lab results easily available on their web page. If they don’t, send a mail and ask. Should be very easy to get. If not, my best advice is to move on to a different brand. Why do different Full Spectrum products contain different cannabinoids ? Different cannabis plant varieties are being used by different producers, and these have different cannabinoid profiles. For example recreational cannabis strains normally have more and higher amounts of different cannabinoids than a typical industrial hemp strain. This due to the flowers of cannabis to be bigger and containing more cannabinoids and terpenes than most industrial hemp strains. Each cannabis strain, both recreational and industrial, has its own profile of cannabinoids. Even plants from the same strain can have a bit different cannabinoid profiles even if they are generally the same. Therefore products made from different strains of cannabis will have different cannabinoid profiles. One extract might have many cannabinoids, and another one will have very few, depending on the genetics of the plant that was used to make it. So, when that is all cleared up, what about Broad and Wide Spectrum? Well broad and wide are terms that kind of means the same. It refers to it being several cannabinoids and even terpenes in the product. Broad spectrum is also used when the oil does not contain any THC. But a broad spectrum oil can also contain THC as one of the several cannabinoids in the product. So broad spectrum still does not say how many cannabinoids are in the product. Some may use this term without necessarily having several cannabinoids in them, just no THC. So here as well, only an actual lab test of the product can tell you how broad the spectrum is and which cannabinoids are present.  Isolates An isolate is the purest form of a compound, which is produced by singularly extracting that compound from its environment and isolating it from all other compounds. So you are left with only the CBD from the plant, eliminating all other cannabinoids and terpenes. This product does not offer any Entourage Effect, as it’s a single compound. Products with very high CBD % are often made from isolates, as a product with that high CBD % made from a plant extract would most lightly get a THC % that is higher than 0.2% and therefore be illegal in most countries. Early on it was believed that pure CBD would have the best effect for most, but this idea has been put aside. A study in 2015 showed that with pure CBD the patient at first got good effect, but that it did not last, While those that used plant extracts and a broader spectrum, had a more lasting stable effect. (1*)  All in all, what have we learned? When it comes down to knowing what is in your product, a lab test is the only way to know. A CBD company should have available lab tests on their web page. Some companies will only say how many mg CBD that are in their dosages, this can be very misleading if you don’t know how to calculate mg to ml over to % CBD. Always ask for the percentage of CBD in the product. In the future there will hopefully be a lot more laboratories available for the public as well, so it’s easier for people to double check their products if they have any doubts. Hope this cleared up a thing or two regarding CBD labeling. Study:*1)OvercomingtheBell‐ShapedDose‐ResponseofCannabidiolbyUsingCannabisExtractEnrichedinCannabidio Could cannabidiol help us cope during stressful times?  We are currently living through anxiety provoking times. The coronavirus is the perfect recipe to turn even the most laid back and centred among us into worrying wrecks, imagining the most catastrophic (although unlikely) outcomes for ourselves and our loved ones. And that, dear friends, is the day-to-day life of someone living with anxiety. I know because for the last fifteen years it’s an inner world I’ve inhabited. Only for me, it’s not a pandemic I’m freaking out about, but lesser evils such as whether I’m going to make a complete idiot of myself in some social gathering or my own favorite anxiety rabbit hole – feeling anxious about feeling anxious. While there’s no magic bullet to banish anxiety for good, managing anxiety symptoms is a commonly stated reason why people take cannabis – medical or otherwise – with CBD showing particular promise in preliminary studies..... read more at ProjectCBD.com by Mari Biles
 Terpenes are scented molecules found in cannabis and many other plants, and responsible for flavour and aroma. Some of the most well-known terpenes found in cannabis are linalool, limonene, pinene, myrcene, and caryophyllene. In addition to providing an aromatic experience, terpenes are believed to contribute to the effects of cannabis, both alone and in combination with cannabinoids. There is a lot of talk about the potential effects of terpenes on the body, but less talk about the mechanisms that explain these effects.... read more Leafly SHIFA PRODUCTS:  Shifa products have added back terpenes from the same flowers used to make our extractions. This to provide you with as much of The Entourage Effect as we can. For high quality CBD Shifa Products, focusing on the Entourage Effect, visit: https://www.shifa-shop.com/shop.html The terpene that calms you down, gives you that relaxing feeling, Myrcene (β-myrcene). It’s typically found in higher amounts in Cannabis indica strains and the effect can be felt in that comfortable lazy stoned effect. High myrcene strains are great for people that need to relax their muscles and a good choice for people with chronic pain and sleep problems. People that need to heal from serious illness often benefit from the sedative effect of myrcenes as well. Even though indica dominant strains othen have the highest amounts, there is also myrcene in sativa plants, just in lower concentrations.  Myrcene is not only found in Cannabis, but in many plants out there. Myrcene is an acyclic monoterpene commonly found in nature in the essential oil of lemongrass (Cymbopogon citratus), hops (Humulus lupus), verbena (Verbena Officinalis), mango (Mangifera Indica), thyme (Thymus Vulgaris), bay (Laurus Nobilis) ,Cannabis and more. B-myrcene is a natural compound with a great safety profile which could significantly improve immune functions, as well as decrease pain sensation in patients suffering from inflammatory, as well as chronic pain.
Given the known anti-inflammatory and antinociceptive effects of cannabis, it is important to discern the qualities that can provide the correct terpene synergy to manage different disorders such as osteoarthritis, neuropathic pain or dermatitis. Although the mechanism of function of myrcene is not fully understood yet, it’s evident it has a promising role in the treatment of inflammation and pain.
Myrcene might help as a : Analgesic – Relieves pain. Antibacterial – Slows bacterial growth. Anti-Diabetic – Helps mitigate the effects of diabetes. Anti-inflammatory – Reduces inflammation systemically. Anti-Insomnia – Aids with sleep. Anti-Proliferative/Anti-Mutagenic – Inhibits cell mutation, including cancer cells. Antipsychotic – Tranquilizing effects relieve symptoms of psychosis. Antispasmodic – Suppresses muscle spasms. As some cannabis strains more than others contain high levels of myrcene, to be on the safer side, it’s smart to choose indica dominant strains. These strains are usually those with a more sedative effect and relaxing high. Some great Indica strains for medical use are: CBD Shark Shock -CBD Crew Seeds Renè -House of the Great Gardener Nordle ( Afgan Skunk ) - Mr.Nice Seeds CBD Critcal Mass
€45.00
€40.00
Grows like a Sativa, flowers like an Indica. Big yielder, like it’s popular origins. Pay attention to supporting the plant during the final stage of flowering, use sticks to prevent branches from breaking or any system you prefer. She can become quite heavy at the top, but you will be happy for harvest!
CBD Shark Shock
€45.00
€40.00
CBD Shark, Mr.Nice Shark Shock crossed with a CBD rich variety to make a unique CBD plant for the Shark lovers. Short and strong plant. Fast flowering and a quite good yielding plant, especially if grown a little longer. Great calming effect, perfect for relaxing and recuperating!
CBD Skunk Haze
€45.00
€40.00
CBD Skunk Haze is a tall plant and quite self supporting, and quite easy to grow. It's a good hybrid and it's one of our most popular strains. Flowers tend to be large and airy, a bit more on the sativa side. Won 3rd place Sativa Cup at TreatingYourself Expo 2013, Ontario, Canada, competing with only high THC plants. Entered by a private grower.
CBD Therapy
€45.00
€40.00
CBD Crew has a world first in releasing this long awaited low THC and high CBD strain. While there are rumors of seed varieties originating out of hemp strains, the CBD Therapy is solely derived from recreational high THC cannabis strains and has taken some 4 years to try stabilize with the use of science. Still some work to do, CBD Crew is now stablizing the seeds even more.
We got the last seeds from 1st addition here and it can variate from 2:1 CBD:THC to 20:1 CBD:THC CBD Crew is sold out! so this is the chance for you to get a hold of this amazing first edition of CBD Therapy, as second edition of CBD Therapy will not be released before April/mai 2017 CBD Nordle
€45.00
€40.00
CBD Nordle is a short and strong Christmas tree shape like plant. She produces dense and compact flowering clusters. One of the calmest most indica dominant strains we have, great for pain relief and muscle spasms. Nice tasty Indica with a relaxing effect!
CBD Mango Haze
€45.00
€40.00
CBD Mango Haze is one of the most pleasant tasting plants in CBD-crew line up, as well as one of the new releases for 2013. CBD Mango Haze has exceeded the ranges of CBD to THC and we have seen plants ranging from the prerequisite 1:1 ratio to as far as 1:2 THC to CBD
CBD OG Kush
€45.00
€40.00
OG Kush is popular strain throughout the world for it's strong effects as a THC plant, but it changes dramatically as a CBD enriched version, CBD OG Kush. Still with the effects of THC, but with a freshness and clarity that is quite high for the normal Kush line.
CBD Yummy
€45.00
€40.00
Strong stemmed and quite self supporting. Gives large cola & beautiful buds. Super cropping recommended to get bigger yields. It can provide very low THC phenos, but mostly 1:1. Grows good both outdoors and indoors. Wonderful slightly uplifting effect, Yummy!
CBD Med Gom 1.0 Autoflower
€35.00
€30.00
CBD Med Gom is the result of a long research and development process carried out by Grass-O-Matic and CBD Crew to obtain a high grade medicinal cannabis strain with the advantages of automatic flowering.
CBD Sweet and Sour Widow
€45.00
€40.00
A CBD enriched White Widow strain, this grows vigorously during the vegetative stage and on flowering produces slightly airy flower clusters, which end highly resinous. The airy start to the bud formation makes this strain more suitable for humid areas where more compact plants would suffer from mould. This strain has a distinct but pleasant odour with a sour onion fragrance.
We at Shifa Shop look forward to even more studies on this terpene, its benefits and its benefits in combination with other terpenes and cannabinoids.
Until then, here are some studies to start off with if you are interested in learning more about Myrcene. Myrcene and terpene regulation of TRPV1 ABSTRACT Nociceptive Transient Receptor Potential channels such as TRPV1 are targets for treating pain.Both antagonism and agonism of TRP channels can promote analgesia, through inactivation andchronic desensitization. Since plant-derived mixtures of cannabinoids and theCannabiscompo-nent myrcene have been suggested as pain therapeutics, we screened terpenes found inCannabisfor activity at TRPV1. We used inducible expression of TRPV1 to examine TRPV1-dependency ofterpene-induced calcium flux responses. Terpenes contribute differentially to calcium fluxes viaTRPV1 induced byCannabis-mimetic cannabinoid/terpenoid mixtures. Myrcene dominates theTRPV1-mediated calcium responses seen with terpenoid mixtures. Myrcene-induced calcium influxis inhibited by the TRPV1 inhibitor capsazepine and Myrcene elicits TRPV1 currents in the whole-cell patch-clamp configuration. TRPV1 currents are highly sensitive to internal calcium. WhenMyrcene currents are evoked, they are distinct from capsaicin responses on the basis of Imaxandtheir lack of shift to a pore-dilated state. Myrcene pre-application and residency at TRPV1 appearsto negatively impact subsequent responses to TRPV1 ligands such as Cannabidiol, indicatingallosteric modulation and possible competition by Myrcene. Molecular docking studies suggesta non-covalent interaction site for Myrcene in TRPV1 and identifies key residues that form partiallyoverlapping Myrcene and Cannabidiol binding sites. We identify several non-Cannabisplant-derived sources of Myrcene and other compounds targeting nociceptive TRPs using a data miningapproach focused on analgesics suggested by non-Western Traditional Medical Systems. Thesedata establish TRPV1 as a target of Myrcene and suggest the therapeutic potential of analgesicformulations containing Myrcene. Myrcene, an Aromatic Volatile Compound, Ameliorates Human Skin Extrinsic Aging via Regulation of MMPs Production-The American Journal of Chinese MedicineVol. 45, No. 05, pp. 1113-1124 (2017) Abstract:Myrcene is an aromatic volatile compound that is commercially well-known as a flavor ingredient in the food industry and a fragrance in the soap and detergent industry. Given the worldwide interest in natural antiphotoaging products, we investigated the protective effects of myrcene in UVB-irradiated human dermal fibroblasts (NHDFs). NHDFs were subjected to 144mJ/cm2of UVB irradiation. The expression of intracellular reactive oxygen species (ROS), matrix metalloproteinase-1 (MMP-1), MMP-3, interleukin-6 (IL-6), transforming growth factor (TGF-β1) and type I procollagen were examined. We showed that myrcene decreased the production of ROS, MMP-1, MMP-3, and IL-6, and increased TGF-β1 and type I procollagen secretions. Furthermore, myrcene treatment (0.1–10μM) dramatically reduced the activation of MAPK-related signaling molecules such as p-ERK, p-p38, and p-JNK and AP-1 including p-c-Jun and p-c-Fos. Our data indicate that myrcene has a potential protective effect on UVB-induced human skin photoaging. Therefore, myrcene might have applications in the skincare industry.Single dose toxicity study of beta-myrcene, a natural analgesic substance.Braz J Med Biol Res. 1990;23(9):873-7. Abstract:The present study was undertaken to provide data on acute toxicity of beta-myrcene, a peripheral analgesic substance found in the essential oils of several plants. Although myrcene has long been used in perfumes and as a food additive, there is almost no information on its toxicological hazards. The acute oral toxicity of myrcene was low in rodents, with approximate lethal doses (ALD) of 5.06 g/kg body weight for mice and greater than 11.39 g/kg body weight for rats. Necropsy data did not reveal any relevant alteration in rats but histopathology findings in mice suggested that the liver and stomach may be target organs for myrcene toxicity after oral administration. Myrcene is highly irritant to the peritoneum, and deaths after intraperitoneal injection of this monoterpene in rats (ALD 5.06 g/kg body weight) and in mice (ALD 2.25 g/kg body weight) were probably due to drug-induced chemical peritonitis. *Terpenes are a diverse class of oils and organic compounds that are produced in many plants as secondary metabolites mainly for defence purposes, but also for favouring pollination. Source: https://www.fundacion-canna.es/en/anti-inflammatory-anti-nociceptive-properties-v-myrcene  Did you know?
It can reduce it both with prior use and use after damage has occurred. When the brain suffers a stroke or a traumatic injury, damage to the brain continues as the brain hemorrhage leads to a snowball effect of inflammation, oxidative stress, and excitotoxicity, or cell death by over-stimulation, usually by the neurotransmitter glutamate. There aren’t many medications that can be given immediately following brain injury or hemorrhage to mitigate these effects, but because the endocannabinoid system (ECS) regulates all of these mechanisms, cannabinoids could be the perfect treatment. .Read more: Rxleaf Such sad news, a worrier that has done more for the CBD movement than most, has left this world. CBSNews: CHARLOTTES WEB  UPDATE FROM PAIGE:
Our family is grateful for the outpouring of love while we mourn the loss of our Charlotte. Charlotte had a catastrophic form of early childhood epilepsy called Dravet syndrome. We are moved by the continual impact that Charlotte’s life has made shedding light on the potential of cannabis for quality of life. We’d like to clarify some of the information that has been shared. Our entire family had been ill for close to a month starting early March, but did not initially fit all of the criteria for COVID-19 testing. For that reason, we were told to self-treat at home unless the symptoms worsened. Charlotte’s symptoms worsened, so she was admitted to the PICU on April 3rd. She was treated on the COVID-19 designated floor using all of the medical protocols set in place. On Friday April 3rd, she was tested, the results were negative for COVID-19 and discharged on Sunday April 5th when she seemingly began to improve. Charlotte had a seizure in the early morning on April 7th resulting in respiratory failure and cardiac arrest. Seizures are not uncommon with illness and paramedics were called returning us to the PICU. Given our family’s month-long history with illness and despite the negative test results, she was treated as a likely COVID-19 case. Her fighting spirit held out as long as it could and she eventually passed in our arms peacefully. We’d like to thank the staff at Children’s Hospital Colorado, Colorado Springs for their swift response and the impeccable and compassionate care that we received. _________ This is Nichole writing to update you for Paige, Greg and Matt. Charlotte is no longer suffering. She is seizure-free forever. Thank you so much for all of your love. Please respect their privacy at this time. What science says about CBD as an anti-viral agent. And, how prohibition is making a bad situation worse. Read more at project CBD here: Project CBD  |
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